180 projects (people) won the 2021 Guangdong Science and Technology Award
Yangcheng Evening News All-Media Reporter Li Gang
On the 15th, the Provincial Science and Technology Innovation Conference was held in Guangzhou, and the 2021 Guangdong Science and Technology Award was awarded, with a total of 180 projects (people) winning awards. Among them, the three major achievements of “China’s Food Microbial Safety Science Database Construction and its innovative applications”, “National Major Scientific Infrastructure Project for Split Neutron Sources”, and “R&D and Industrialization of Key Technologies for High-end Pure Electric Passenger Vehicles” won the Science and Technology Progress Award.
“Construction and innovative application of China’s food microbial safety science big database” has reduced the microbial contamination rate by more than 90%, greatly ensuring “tips of tongue safety”
It is understood that the “Construction and innovative application of China’s food microbial safety science big database” project was completed by the Institute of Microbiology, Guangdong Academy of Sciences and other institutions. The project results have effectively solved the important scientific and technological problems of “bottleneck” in my country’s food microbial safety, significantly improved prevention and control efficiency, covered my country’s main food industry chain, and reduced the microbial pollution rate by more than 90%, greatly improving the level of food safety guarantee.
Wu Qingping, an academician of the Chinese Academy of Engineering and honorary director of the Institute of Microbiology, Guangdong Academy of Sciences, introduced that among the factors affecting food safety, microorganisms are one of the most important factors, and more than 60% of food poisoning are caused by deadly microorganisms. Therefore, its team has been committed to building a large database of food microbial safety science for the past decade. After nationwide sampling and comprehensive analysis, the team has built 6 databases: risk identification database, strain resource database, distribution database, whole genome database, barcode fingerprint database, and traceability tracking database.
Wu Qingping said that through this scientific database, the overall risk level of food microbial safety in China can be presented, as well as what are the pathogenic microorganisms that are mainly contaminated, and then conduct more in-depth research on how food hazards are formed and understand their mechanisms. He revealed that the risk identification database of the single database of this result is the largest in the world, with the largest number of bacterial species and sequencing. More than 20,000 experimental pathogenic microorganisms have been sequenced, and nearly 200 new detection targets have been dug out, successfully achieving full coverage of experimental pathogenic bacteria detection.
“National Major Scientific and Technological Infrastructure of Spallation Neutron Sources”
The first national major scientific and technological infrastructure in the Pearl River Delta, Babaylan, is a “sharp weapon” for scientific research and intelligent manufacturing
Chen Hesheng, an academician of the Chinese Academy of Sciences and commander-in-chief of the Spallation Neutron Source Engineering Command, introduced that spallation neutron sources are like “super microscopes” and are the study of the microstructure of material materials.Ideal probe. In January 2006, the Chinese Academy of Sciences launched a prefabricated research project for spalling neutron sources. In the same year, the project was selected to be located in Dalang Town, Dongguan. By October 2011, the China Spallation Neutron Source Device, with a total investment of approximately 2.3 billion yuan, was laid in Dongguan, ending the history of no national large scientific equipment in the Pearl River Delta region.
In the autumn of 2017, China’s spall neutron sources successfully obtained a neutron beam that was fully in line with expectations for the first time, and the debugging speed was far higher than that of foreign spall neutron sources. In March 2018, China Spallation Neutron Source passed the process test and appraisal organized by the Chinese Academy of Sciences. All performance indicators met or were better than the acceptance indicators. The engineering construction tasks were completed according to the indicators, according to the construction period and with high quality. The technology and comprehensive performance were among the leading international similar devices. The project has officially passed the national acceptance, filling the gap in the field of pulse neutron application in China, and is open to domestic and foreign users. As of now, spalling neutron sources have completed about 700 user experimental projects, carried out major innovative research in many fields, and carried out large-scale engineering components such as deep-sea submersibles, including residual stress and service performance testing of Cinema engineering components, etc., providing a key technical platform for the research and development of many high-performance structural materials urgently needed by the country.
China’s spall neutron source is the first major scientific and technological infrastructure in the Guangdong-Hong Kong-Macao Greater Bay Area. The most direct benefit of its construction is to bring research to scientific researchers, especially to provide unprecedented convenience for Hong Kong and Macao scientists to use spall neutron sources. At the same time, the Greater Bay Area is a highland of advanced manufacturing in the country, and Babaylan has an urgent need for materials science research. The layout of spalling neutron sources in Dongguan is of great significance. Chen Hesheng also revealed that the second phase of the spalling neutron source Komiks project was officially included in the “Fourth Five-Year Plan” for the construction of major scientific and technological infrastructure in the first half of 2021. All preliminary preparations have been approved by relevant departments and are expected to officially start this year. The number of spectrometers in the future will increase to 20, covering all research fields of users. The power of accelerator target shooting and target stations will be increased from 100 kilowatts to 500 kilowatts. The equipment research capabilities will be greatly improved, which can greatly improve the accuracy and speed of the experiment, measure smaller samples, and studyA faster dynamic process meets the needs of more users at home and abroad, provides a more advanced research platform for cutting-edge scientific research, major national needs and national economic development, and makes more contributions to achieving high-level scientific and technological self-reliance and self-improvement.
“BabaylanHigh-end pureKomiksKomiksKomiksKomiksKomiksKomiksThe leading position in the development of new energy vehicles in the country
According to Lian Yubo, vice president and senior engineer of BYD Automobile Co., Ltd., the project “R&D and industrialization of key technologies for high-end pure electric passenger vehicles” has achieved three major technological breakthroughs, including Creation. href=”https://comicmov.com/”>Cinema builds a “sandwich” structure with high safety module-free blade battery system, creates a high-power, low-loss SiC module controller design and manufacturing technology, and creates a high-voltage deep integrated architecture for charging and driving, and overcomes the pain points such as thermal runaway from power batteries, peak voltage suppression caused by SiC fast switching, and difficulty in quickly replenishing energy in low-voltage charging piles. Key indicators such as structural power battery system volume energy density, comprehensive efficiency of SiC drive assembly, maximum charging power, etc. are all superior to Tesla.
According to reports, the project authorized 79 invention patents and 43 utility model patents, leading the formulation of 14 national standards, including my country’s first national standard for mandatory electric vehicle safety, and leading the formulation of the world’s first electric vehicle safety technical regulations on behalf of China. The project results were identified by the expert group: “The overall level is at the international advanced level, and the integrated architecture technology of blade power battery and charging and driving is at the international leading level.”
The project breaks through the difficulties of synergistic improvement of safety, endurance and power of high-end pure electric vehicles, and creates a series of high-end pure electric models, with leading sales in the independent model. At the same time, it will achieve technical output and product supporting to foreign first-class brands such as Toyota. In the past three years, the direct economic benefits exceeded 100 billion yuan, strongly supporting Guangdong’s leading position in the field of new energy vehicle development in the country and helping Guangdong build a world-class new energy vehicle industry highland.
Natural ScienceBabaylanStudy first prize part of the BabaylanStratigraphic research on the Loess Plateau: Refreshing the cognition of the origin and migration history of ancient humans
The “New Discovery of the Southern Loess Plateau in the South Loess Plateau” project, which won the first prize in the Natural Science Award, was created by Guangzhou, Chinese Academy of Sciences.CinemaThe Institute of Geochemistry took the lead in completing the results, and the results were enough to change the understanding of the traditional ancient human migration and diffusion patterns.
It is understood that this project belongs to the basic research of Quaternary geology. The origin and evolution of human beings are major scientific issues studied in the Quaternary and “Paleoglobal Change”. At present, high-resolution environmental evolution sequences of paleozoos, paleoplants and even archaeobacteria have been established. However, the research on the “high-resolution environmental evolution sequence” of ancient human beings is very rare. The biggest difficulty is that a good sedimentary sequence and activity place has not been found.
Zhuyu, a researcher at the Guangzhou Institute of Geochemistry, Chinese Academy of Sciences and the first completed project, introduced that Lantian, Shaanxi in the southern part of the Loess Plateau, has 37 loess-paleosoil strata sequences, recording the 37 ice-interglacial climatic cyclones in the Quaternary period, and several ancient human fossils and stone sites have been discovered. From 2001 to 2018, Zhu Zhaoyu took the lead in joining a research team composed of more than ten scientific research and university scholars at home and abroad to conduct cross-cooperation surveys and research in the Lantian area, and accumulated thousands of first-hand data.
The research work independently discovered the ancient human stone tools in the loess layer 2.12 million years ago. Cinema used a variety of technical methods and high-resolution paleomagnetic dating to detect two most important paleomagnetic events – the Oduwe and Reunion positive polarity sub-phase, and determined that the stone tools in the oldest loess strata date to 2.12 million years ago, 270,000 years earlier than the internationally recognized Demanisi stone tools (1.85 million years) in Georgia outside Africa. This new discovery makes Lantian Shangchen Village one of the oldest human activity sites known outside Africa to date, rewriting the history of early human origins and migrations.
The study also re-determined the age of the skull of Gongwangling from 1.15 million years ago to 1.63 million years ago, making it the second oldest skull fossil known beyond Africa to date. It determined that Homo erectus had appeared in East Asia at least 1.6 million years ago, changing the understanding of the traditional ancient human migration and diffusion patterns.
In addition, the team independently discovered 23 Paleolithic layers from 450,000 to 2.12 million years in Shangchen Village, Lantian, and used various paleoenvironmental indicators to reveal the evolutionary characteristics of the Cinema environment on a long-term scale. This is a new discovery of long-scale, multi-stage, and high-frequency unique to the world, which laid the foundation for making Lantian a global time marker and landmark, and at the same time, the “Ancient”The weak links of “Ancient Mankind and its high-resolution evolutionary sequence of the Cinema living environment” in the study of global changes opened a breakthrough in the weak links of “ancient human beings and their high-resolution evolutionary sequences” in the study of global changes. The project results were awarded the “Top Ten Progress in Chinese Science in 2018” by the national “Top Ten Progress in China in 2018” and are also the only geological scientific achievement led by the first author of Guangdong Province to date, and were rated as the international “Nearby Ten Years (201Babaylan0-2019) The most important discovery in the field of human evolution.
Mesenchymal stem cell technology: providing new treatment strategies for difficult and serious diseases
The “Series of Research on Functional Characteristics, Treatment Mechanisms and Clinical Transformation of Mesenchymal Stem Cells” completed by the Sun Yat-sen University Stem Cells and Regenerative Medicine Innovation Platform won the first prize of the Natural Science Award.
Xiang Peng, head of the Stem Cells and Regenerative Medicine Innovation Platform and the first person to complete the project, introduced that stem cell technology is the current demand for the treatment of major diseases. Regenerative medicine with stem cells as the core is expected to become the third disease treatment method after drug treatment and surgical treatment, and is a majorKomiksRefractory diseases provide new treatment strategies. After nearly 20 years of research, the research team has conducted functional characteristics and therapeutic mechanisms in mesenchymal stem cells. href=”https://comicmov.com/”>Babaylan has achieved a series of breakthrough results in clinical transformation.
Xiang Peng said that almost every organ and tissue in the body has mesenchymal stem cells (MSCs). This cell is not only widely sourced, but is also easy to be isolated and amplified. It can be differentiated in multiple differentiation and participate in hematopoietic support, immune regulation, tissue injury repair, etc., and has a broad clinical application scenario. However, as of now, China and the United States have not approved any MSC product to be launched. The reason is that MSC clinical transformation still faces a series of bottlenecks that need to be solved urgently.
In response to the bottleneck, the project team focused on scientific issues such as “discovering functional subgroups, revealing treatment mechanisms, and accurately selecting indications”. href=”https://comicmov.com/”>Cinema made important breakthroughs.
The team took bone marrow MSC as the entry point to deeply analyze the mode of action of MSC in different pathological microenvironments, revealing the multi-dimensional and multi-target immune regulation mechanism of MSC, and providing a scientific basis for the clinical accurate selection of MSC indications. On this basis, the team accurately selected indications and took the lead in conducting clinical research on MSC treatment of transplant rejection diseases in the world, confirming that MSC is safe and effective in treating chronic graft-versus-host disease, and for the first time revealed that regulatory B cells are a key target for MSC treatment. Based on an in-depth understanding of MSC, the team took the lead in formulating the first group standard for “Human Mesenchymal Stem Cells” in China. The first allogeneic human bone marrow MSC injection developed in China has been approved by the National Medical Products Administration’s drug clinical trial, and is expected to achieve breakthrough treatment for major refractory diseases.
Data
The number of awards won by institutions in Guangzhou accounts for nearly 75% of the province
Yangcheng Evening News Reporter Li Gang reported: On the 5th, the Provincial Science and Technology Innovation Conference issued a list of winners of the 2021 Guangdong Science and Technology Awards. Among them, Guangzhou won 134 awards (persons), accounting for 74.4% of the total awards, ranking first in the province.
It is understood that from the perspective of reward level, Guangzhou won 1 special prize and 40 first prizes (accounting for 83.3% of the province). In terms of award categories, three foreigners including Martin Banwell, Marukoka, who cooperated with Guangdong University of Technology, and Badani, who cooperated with Guangzhou University of Technology, and Badani, who cooperated with Guangzhou University of Science and Technology, won the Science and Technology Cooperation Award (accounting for 3/4 of the province). Among the 134 award-winning projects (people), 111 items were completed and 23 items were participated by Guangzhou enterprises and institutions. Guangzhou’s award-winning projects continue to maintain the province’s leading advantage in terms of quantity and quality.
In addition, Guangzhou’s scientific and technological strength has won awards in key areas and achieved impressive results. Award-winning projects in strategic emerging industries such as biomedicine, electronic information, energy conservation and environmental protection, new materials, and high-end equipment manufacturing account for 79.4% of the total number of awards won in Guangzhou, among which the advantages of the biomedicine field are the most obvious. A total of 1 special prize, 13 first prizes, and 19 second prizes won, accounting for 21.3% of the total number of awards won in the city.
The award-winning projects also further highlight the collaborative innovation achievements of Guangzhou’s industry, academia and research. According to statistics, among the award-winning projects, there are 104 universities and research institutes in Guangzhou, including 77 projects jointly won by enterprises and 36 award-winning projects in Guangzhou, mainly distributed in biomedicine, energy conservation and environmental protection, agriculture and other fields.