180 projects (people) won the 2021 Guangdong Science and Technology Award
Yangcheng Evening News All-Media Reporter Li Gang
On the 15th, the Provincial Science and Technology Innovation Conference was held in Guangzhou, and the 2021 Guangdong Science and Technology Award was awarded, with a total of 180 projects (people) winning awards. Among them, the three major achievements of “Construction of China’s Food Microbial Safety Science Database and Its Innovative Application”, “National Major Scientific Infrastructure Project for Split Neutron Sources”, and “Research and Development and Industrialization of Key Technologies for High-end Pure Electric Passenger Vehicles” won the Science and Technology Progress Award.
“Construction and innovative application of China’s food microbial safety science database”
Reduced the microbial pollution rate by more than 90%, greatly ensuring the “tips of tongue safety”
It is understood that the “Construction and innovative application of China’s food microbial safety science database” project was completed by the Institute of Microbiology, Guangdong Academy of Sciences and other institutions. The project results have effectively solved the important scientific and technological problems of “bottleneck” in my country’s food microbial safety, significantly improved prevention and control efficiency, covered my country’s main food industry chain, and reduced the microbial pollution rate by more than 90%, greatly improving the level of food safety guarantee.
Wu Qingping, an academician of the Chinese Academy of Engineering and honorary director of the Institute of Microbiology, Guangdong Academy of Sciences, introduced that among the factors affecting food safety, microorganisms are one of the most important factors, and more than 60% of food poisoning are caused by deadly microorganisms. Therefore, its team has been committed to building a large database of food microbial safety science for the past decade. After nationwide sampling and comprehensive analysis, the team has built 6 databases: risk identification database, strain resource database, distribution database, whole genome database, barcode fingerprint database, and traceability tracking database.
Wu Qingping said that through this scientific database, the overall risk level of food microbial safety in China can be presented, as well as what are the pathogenic microorganisms that are mainly contaminated, and then conduct more in-depth research on how food hazards are formed and understand their mechanisms. He revealed that the risk identification database of the single database of this result is the largest in the world, with the largest number of bacterial species and sequencing. More than 20,000 experimental pathogenic microorganisms have been sequenced, and nearly 200 new detection targets have been dug out, successfully achieving full coverage of experimental pathogenic bacteria detection.
“National Major Scientific and Technological Infrastructure of Spallation Neutron Sources”
The first national large scientific facility in the Pearl River Delta, a “weapon” for scientific research and intelligent manufacturing
Chen Hesheng, an academician of the Chinese Academy of Sciences and commander-in-chief of the Spallation Neutron Source Engineering Command, introduced that spallation neutron sources are like “super microscopes” and are an ideal probe for studying the microstructure of material materials. In January 2006, the Chinese Academy of Sciences launched a prefabricated research project for the source of scattered neutrons. In the same year, the project was chosen to settle in Dalang Town, Dongguan. By October 2011, China’s total investment of approximately RMB 2.3 billion isBabaylanThe cracked neutron source device was laid in Dongguan, ending the history of no national large scientific equipment in the Pearl River Delta region.
In the autumn of 2017, China’s spalled neutron source successfully obtained a neutron beam that was fully in line with expectations for the first time, and the debugging speed was far higher than that of foreign spalled neutron sources. In March 2018, China’s spalled neutron source passed the Chinese Academy of SciencesKomiksProperty structural materials research provides a key technology platform.
China’s spalling neutron source is the first major scientific and technological infrastructure in the Guangdong-Hong Kong-Macao Greater Bay Area. The most direct benefit of its construction is to bring research to scientific researchers, especially to provide unprecedented convenience for Hong Kong and Macao scientists to use spalling neutron sources. At the same time, the Greater Bay Area is a national advanced manufacturing highland, and researches on materials scienceKomiks. The layout of the spall neutron source in Dongguan is of great significance. Chen Hesheng also revealed that the second phase of the spall neutron source project was officially included in the “14th Five-Year Plan” for the construction of major scientific and technological infrastructure in the first half of 2021. All preliminary preparations have been approved by relevant departments and are expected to be officially started this year. The number of spectrometers in the future will increase to 20, covering all research fields of users. The power of accelerator target shooting and target stations will be increased from 100 kilowatts to 500 kilowatts, and the equipment research capabilities will be greatly improved. href=”https://comicmov.com/”>Babaylan greatly improves the accuracy and speed of the experiment, measures smaller samples, studies faster dynamic processes, meets the needs of more users at home and abroad, and provides more for cutting-edge scientific research, major national needs and national economic development.Advanced research platform makes more contributions to achieving high-level scientific and technological self-reliance.
“Research and development and industrialization of key technologies for high-end pure electric passenger cars” support Guangdong’s leading position in the field of new energy vehicle development in the country
According to Lian Yubo, vice president and senior engineer of BYD Automobile Co., Ltd., the “Research and development and industrialization of key technologies for high-end pure electric passenger cars” project has achieved three major technological breakthroughs, including the creation of a “SanmingCinema breaking point, including the creation of a “SanmingCinema structure high-safe module blade battery system, the creation of a high-power, low-loss SiC module controller design and manufacturing technology, and the creation of a charging and driving integrated high-voltage deep integrated architecture, which has overcome the dynamics. href=”https://comicmov.com/”>KomiksThe thermal runaway from power battery, the peak voltage suppression caused by SiC fast switch, and the difficulty of quickly replenishing energy in low-voltage charging piles. Key indicators such as structural power battery system volume energy density, comprehensive efficiency of SiC drive assembly, maximum charging power, etc. are all superior to Tesla. According to reports, the project authorized 79 invention patents and 43 utility model patents, leading the formulation of 14 national standards, including my country’s first national standard for mandatory electric vehicle safety, and leading the formulation of the world’s first electric vehicle safety technical regulations on behalf of China. The project results were identified by the expert group: “The overall level is at the international advanced level, and the integrated architecture technology of blade power battery and charging and driving is at the international leading level.”
The project breaks through the problems of high-end pure electric vehicle safety, battery life, and power coordination improvement, and creates a series of high-end pure electric models, with leading sales in the independent vehicle model. At the same time, it will achieve technical output and product supporting to foreign first-class brands such as Toyota. In the past three years, the direct economic benefits exceeded 100 billion yuan, strongly supporting Guangdong’s leading position in the field of new energy vehicles in the country and helping Guangdong build a world-class new energy industry highland.
Part 1 Prize of Natural Science Awards
LoessPlateau strata research: Refreshing the cognition of the origin and migration history of ancient humans
The project “Age of the Loess Stratigraphy and Paleoenvironment and its Early Human Evolution in the Southern Loess Plateau” which won the first prize in the Natural Science Award was led by the Guangzhou Institute of Geochemistry, Chinese Academy of Sciences. The results are enough to change the understanding of the traditional migration and diffusion patterns of ancient humans.
It is understood that this project belongs to the basic research of Quaternary geology. The origin and evolution of human beings are major scientific issues studied in the Quaternary and “palaeoglobal changes”. High-resolution environmental evolution sequences of paleozoos, paleoplants and even archaeobacteria have been established. However, the study of “high-resolution environmental evolution sequences” of ancient human beings is very rare. The biggest difficulty is that a good sedimentary sequence and activity place has not been found.
Zhuyu, a researcher at the Guangzhou Institute of Geochemistry, Chinese Academy of Sciences and the first completed project, introduced that Lantian, Shaanxi in the southern part of the Loess Plateau, has 37 loess-paleosoil strata sequences, recording the 37 ice-interglacial climatic cyclones in the Quaternary period, and several ancient human fossils and stone sites have been discovered. From 2001 to 2018, Zhu Zhaoyu took the lead in joining a research team composed of more than ten scientific research and university scholars at home and abroad to conduct cross-cooperation surveys and research in the Lantian area, and accumulated thousands of first-hand data.
The research work independently discovered the ancient human stone in the loess layer 2.12 million years ago. It used a variety of technical methods and high-resolution paleomagnetic dating to detect two most important paleomagnetic events – the Oduwee and Reunion positive polarity sub-phase, and determined that the stone tool in the oldest loess formation was 2.12 million years ago, 270,000 years earlier than the internationally recognized Demanisi stone tool (1.85 million years) in Georgia, which is the internationally recognized internationally. This new discovery makes Lantian Shangchen Village one of the oldest human activity sites known outside Africa to date, rewriting the history of early human origins and migrations.
The study also re-determined the Komiks bone age from 1.15 million years ago to 1.63 million years ago, making it the second oldest skull fossil known to Africa so far. It determined that Homo erectus had appeared in East Asia at least 1.6 million years ago, changing its understanding of the traditional ancient human migration and diffusion patterns.
In addition, the team independently discovered 23 Paleolithic layers from 450,000 to 2.12 million years in Shangchen Village, Lantian, and used various paleoenvironmental indicators to reveal the evolutionary characteristics of the living environment of ancient humans on a long-term scale. This is the long scale unique to the world as we know it, multi-stage, high-frequency new discoveries have laid the foundation for making Lantian a global time marker and landmark, and opened a breakthrough in the weak links of “high-resolution evolutionary sequences of ancient humans and their living environment” in the study of “paleoglobal changes”.
The project results were awarded the national “Top Ten Progress in Chinese Science in 2018”, and are also the only geological scientific achievement led by the first author of Guangdong Province to date, and were rated as the “most important discovery in the field of human evolution in the past decade (2010-2019).
Mesenchymal stem cell technology: providing new treatment strategies for difficult and serious diseases
The “Series of Research on Functional Characteristics, Treatment Mechanisms and Clinical Transformation of Mesenchymal Stem Cells” project completed by Sun Yat-sen University’s Stem Cells and Regenerative Medicine Innovation Platform won the first class of the Natural Science Award Komiks Award.
Xiang Peng, head of the innovation platform for stem cell and regenerative medicine at Sun Yat-sen University and the first person to complete the project, introduced that stem cell technology is currently the need for the treatment of major diseases. Regenerative medicine with stem cells as the core is expected to become the third disease treatment method after drug treatment and surgical treatment, providing new treatment strategies for major refractory diseases. After nearly 20 years of research, the research team has achieved a series of breakthrough results in the functional characteristics, therapeutic mechanism and clinical transformation of mesenchymal stem cells. Xiang Peng said that almost every organ and tissue in the body has mesenchymal stem cells (MSCs). This cell not only has a wide range of sources, but is also easy to be isolated and amplified. It can differentiate multiple times and participate in hematopoietic support, immune regulation, tissue damage repair, etc., and has a broad clinical application scenario. However, as of now, neither China nor the United States have approved any MSC product to be launched. The reason is that MSC clinical transformation still faces a series of bottlenecks that need to be solved urgently.
In response to the bottleneck, the project team has cooperated to solve scientific issues such as “discovering functional subgroups, revealing treatment mechanisms, and accurately selecting indications”, and has made important breakthroughs.
The team took bone marrow MSC as the entry point to deeply analyze the mode of action of MSC under different pathological microenvironments, revealing the multi-dimensional and multi-target immune regulation mechanism of MSC, providing a scientific basis for the clinical accurate selection of MSC indications. On this basis, the team accurately selected indications and took the lead in the international clinical research on the treatment of transplant rejection diseases, confirming MSC treatmentChronic graft-versus-host disease is safe and effective, and it is revealed for the first time that regulatory B cells are a key target for MSC treatment. Based on an in-depth understanding of MSC, the Cinema team took the lead in formulating the first “Human Mesenchymal Stem Cell” group standard in China. The first allogeneic human bone marrow MSC injection developed in China has been approved by the National Medical Products Administration’s drug clinical trial, and is expected to achieve breakthrough treatment for major refractory diseases.
Data
The number of awards won by institutions in Guangzhou accounts for nearly 75% of the province
Yangcheng Evening News Reporter Li Gang reported: On the 15th, the Provincial Science and Technology Innovation Conference presented the list of winners of the 2021 Guangdong Science and Technology Awards. Among them, Guangzhou won 134 awards (persons), accounting for 74.4% of the total awards, ranking first in the province.
It is understood that from the perspective of reward level, Guangzhou won 1 special prize and 40 first prizes (accounting for 83.3% of the province). In terms of award categories, three foreigners including Martin Banwell, Marukoka, who cooperated with Guangdong University of Technology, and Badani, who cooperated with Guangzhou University of Technology, and Badani, who cooperated with Guangzhou University of Science and Technology, won the Science and Technology Cooperation Award (accounting for 3/4 of the province). Among the 134 award-winning projects (people), 111 items were completed and 23 items were participated by Guangzhou enterprises and institutions. Guangzhou’s award-winning projects continue to maintain the province’s leading advantage in terms of quantity and quality.
In addition, Guangzhou’s scientific and technological strength has won awards in key areas and achieved impressive results. The winning projects in strategic emerging industries such as medicine, electronic information, energy conservation and environmental protection, new materials, and high-end equipment manufacturing account for 79.4% of the total number of awards won in Guangzhou, among which the advantages of the biomedicine field are the most obvious. A total of 1 special prize, 13 first prizes, and 19 second prizes won, accounting for 21.3% of the total number of awards won in the city.
The award-winning projects also further highlight the collaborative innovation achievements of Guangzhou’s industry, academia and research. According to statistics, among the award-winning projects, there are 104 universities and research institutes in Guangzhou, including 77 projects jointly won by enterprises and 36 award-winning projects in Guangzhou, mainly distributed in biomedicine, energy conservation and environmental protection, agriculture and other fields.