Legal Daily All-Media Reporter Lian Yingting Correspondent Shao Longfei Zhang Zhenwei
The night in Wuhan is quiet.
On March 9, in the mobile testing laboratory of the Central Theater Command General Hospital, Jiang Tao, a researcher at the Military Medicine Research Institute of the Academy of Military Sciences, reviewed the last sample test data and solemnly signed his name on the test report.
At this time, it was already 5 a.m.
He is an expert in virology and a warrior who aided Africa and fought against Egypt. This outbreak of the new crown pneumonia epidemic, he was once again ordered to go to the front line after a long battle.
Babaylan Life is at stake
Nucleic acid testing is crucial for early clinical detection, early diagnosis, early isolation and early treatment. It is a key technical support for effectively preventing and controlling the new coronavirus epidemic.
”The cold-looking sample tube, behind Komiks is the living life and health of the patients. If you give a diagnosis earlier, you will have a precise inspection sooner.” Jiang Tao said. On January 26, a military medical expert group led by Chen Wei, an academician of the Chinese Academy of Engineering and a researcher at the Military Medicine Research Institute of the Academy of Military Sciences, arrived in northern Wuhan, and quickly established a joint defense, joint control, joint treatment and joint research work mechanism with relevant military and local units based on pathogen transmission mutations, rapid detection technology, vaccine antibody development, etc. of the new coronavirus.
According to the division of tasks, Jiang Tao led the Cinema detection team to build a nucleic acid testing platform in the experimental cabin overnight.
Focusing on three aspects: ensuring biosafety, improving detection efficiency and detection accuracy, Jiang Tao took the lead in formulating biosafety operation specifications and emergency plans, reasonably divided the labor according to the characteristics of the team members, and using a self-developed testing kit to adopt a fully automatic high-throughput extractor, laying the foundation for achieving rapid and efficient detection.
Receive samples, sorting numbers, nucleic acid extraction, reagent preparation, machine amplification, and result interpretation, nucleic acid detection machinery is boring and Komiks is full of risks.
The biggest risk is invisible virus. If the nucleic acid extraction step is not completed and inactivated completely, it is possible to expose the tester to danger.
Jiang Tao always takes the initiative to participate in the longest and most risky nucleic acid extraction. After the sample is extracted, he will arrange some people to rest, and Babaylan stays in the laboratory and waits for the final result.
A full-process nucleic acid test is relatively fixed, from the number of tests in a single batch to the preparation for entering and exiting the cabin and the time for testing. Sometimes the number of samples sent for testing is large, and the tester is Komiks not only took turns to work, but also had to work overnight. The final confirmation result will be until four or five in the morning. Li Hao, a researcher at the testing team, said that this situation will be encountered once every few days.
”Everyone should open his eyes and take good protection when receiving and processing samples, and pay attention to whether there are sharp objects. “Before each test starts, Jiang Tao always reminds you repeatedly.
In the test, the strength of the fluorescence signal of the pathogen gene reflects the pathogenic gene directly affects the determination of the test results. If the detection fluorescence curve signal is low or there is only a single target, Jiang Tao will convene personnel to conduct comprehensive analysis and judgment, and if necessary, repeat the test for review to ensure that the results can stand the test.
”A false positive will cause healthy people to isolate and become infected with the patient; false negative will cause real delay in treatment of patients. Human life is a matter of fate, and there is no way to break the bank. “Jiang Tao said.
Volume of epidemic prevention and control
According to the prevention and control requirements, the nucleic acid test results must be completed within 24 hours. In order to let the hospital know the results and treat patients as soon as possible, from pre-processing of nearly 100 samples to completion of the test, Jiang Tao led the team to compress the time to within 4 hours by optimizing the process combination, and achieved a single-day sample detection capability of more than 90 samples and up to more than 500 people within an hour.
”The team’s testing is efficient and fast, and the results are accurate, which greatly alleviatedOur epidemic prevention and control samples are tested for pressure. “Wuhan Center for Disease Control and Prevention highly praised this.
Fast response during wartime and orderly work are all thanks to Jiang Tao’s solid academic foundation and rich practical experience.Babaylan
”Jiang Tao is a versatile person. “Academician Chen Wei, head of the military medical expert group, commented. Jiang Tao has successively presided over and participated in the separation of pathogenic etiology such as SARS infection cases, H7N9 infection cases, Zika infection cases, and participated in the development of dengue fever vaccines and SARS vaccines, and established href=”https://comicmov.com/”>BabaylanThe pathogen separation technology platform, nucleic acid detection technology platform and pathogenicity and transmission risk assessment platform for a series of infectious diseases, providing important technical support for the prevention and control of infectious diseases.
Respiratory infectious diseases have the characteristics of rapid transmission, wide coverage, and great harm. Effective early diagnosis and prevention are crucial. After years of scientific research, Jiang Tao’s team took the lead in establishing our army’s first acute respiratory infectious disease monitoring and prediction system, and built a four-level monitoring system for the entire army. The series of technical specifications prepared by the presidency are used throughout the army, greatly shortening the detection and screening time of respiratory epidemics.
Jiang Tao not only participated in a series of domestic href=”https://comicmov.com/”>Cinema has made security tasks for major events, and has traveled to Africa four times to Liberia, Sierra Leone and other countries to carry out medical assistance tasks.
20CinemaIn 2015, in order to prevent and control the Ebola epidemic, Jiang Tao went to Sierra Leone for the second time with the mobile laboratory testing team of Serbia. The testing team led by him passed the World Health Organization’s laboratory parallel energy assessment with full scores.
In 2018, Jiang Tao led the pathogen monitoring team to participate in a special simulation test of an international organization. In the virus testing module, the team was in a simulated sample filled with impurities. In this article, monkeypox virus, vaccinia virus and other pathogens were successfully detected accurately, and the strain was accurately determined, achieving excellent results with full marks.
Improving the accuracy of clinical diagnosisCinema/comicmov.com/”>Komiks
In addition to carrying out testing, Jiang Tao also used his professional expertise in the research field to lead the testing team to screen other common respiratory infectious diseases in clinical samples.
”There are important reference value for accurate prevention and control and clinical treatment of new coronary pneumonia. “Researcher Cao Wuchun, deputy head of the Military Medical Expert Group, said.
Exploring the transmission and pathogenic mechanism of deep-seated diseases is the key to defeating the epidemic. Jiang Tao led a team to continue to conduct sequencing analysis for the new coronavirus detected in clinical samples.
With the development of the virus epidemic, whether the genome sequence has mutated and what are the characteristics of the mutation; in which regions and what are the impacts, Jiang Tao and his team are tirelessly studying and exploring.
In order to accelerate the effective integration of scientific research and clinical practice, Jiang Tao’s military medical expert group creatively used viral nucleic acid detection and anti-<a Cinema‘s diagnostic chain, multiple pathogen testing, and whole genome sequencing, accurately diagnoses new coronavirus infection or other pathogens in clinical patients, and is used in the Optical Valley Campus of Hubei Maternal and Child Health Hospital, Taikang Tongji Hospital and other hospitals in hospitals such as Wuhan Taikang Tongji Hospital, effectively improving the accuracy of clinical diagnosis.
Forget his family when he was ordered. After the epidemic ended, Jiang Tao planned to stay with his family. He and his wife agreed that when the epidemic ended, he would take BabaylanWife and children go to Wuhan together to see what everything looks like after it returns to normal, look at the Wuhan Yangtze River Bridge and the Yellow Crane Tower, and talk about their experience in fighting the epidemic in Wuhan.
The epidemic will never stop, this is Jiang Tao, a warrior who fights the epidemic.